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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
33.03
Human Site:
S656
Identified Species:
51.9
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S656
L
Y
E
P
Q
V
N
S
P
K
D
F
T
E
G
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
V621
S
L
I
K
N
A
K
V
Q
K
R
G
K
I
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S687
L
Y
E
P
Q
V
N
S
P
K
D
F
T
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S656
L
Y
D
P
Q
V
N
S
P
K
D
F
T
E
G
Rat
Rattus norvegicus
Q9JJ31
780
90872
S656
L
Y
D
P
Q
V
N
S
P
K
D
F
T
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
S655
L
Y
E
P
Q
V
N
S
P
K
D
F
T
E
G
Chicken
Gallus gallus
XP_417163
809
94020
S685
L
Y
E
P
Q
V
N
S
P
K
D
F
T
E
G
Frog
Xenopus laevis
Q6GPF3
768
88937
I653
K
E
P
K
S
K
E
I
E
S
G
H
M
F
T
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S656
S
Y
E
P
V
V
G
S
P
K
D
F
A
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
L661
S
S
D
N
E
N
S
L
T
P
E
S
T
V
E
Honey Bee
Apis mellifera
XP_623958
789
91733
S665
L
V
E
P
H
A
H
S
P
K
D
F
A
N
D
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
T639
L
C
D
V
P
S
T
T
V
T
A
R
D
F
T
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
S663
L
M
Q
P
E
A
K
S
P
K
E
F
V
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Q631
P
N
T
K
T
V
S
Q
N
D
A
F
E
F
N
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
P685
G
L
D
A
L
V
K
P
E
T
Q
F
K
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
93.3
N.A.
100
100
0
73.3
N.A.
6.6
53.3
6.6
46.6
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
100
100
0
73.3
N.A.
33.3
60
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
20
0
0
0
0
14
0
14
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
0
0
0
7
54
0
7
7
7
% D
% Glu:
0
7
40
0
14
0
7
0
14
0
14
0
7
47
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
74
0
20
0
% F
% Gly:
7
0
0
0
0
0
7
0
0
0
7
7
0
0
54
% G
% His:
0
0
0
0
7
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
7
0
0
0
0
0
7
0
% I
% Lys:
7
0
0
20
0
7
20
0
0
67
0
0
14
0
0
% K
% Leu:
60
14
0
0
7
0
0
7
0
0
0
0
0
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
7
7
7
40
0
7
0
0
0
0
7
14
% N
% Pro:
7
0
7
60
7
0
0
7
60
7
0
0
0
0
0
% P
% Gln:
0
0
7
0
40
0
0
7
7
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% R
% Ser:
20
7
0
0
7
7
14
60
0
7
0
7
0
0
7
% S
% Thr:
0
0
7
0
7
0
7
7
7
14
0
0
47
0
14
% T
% Val:
0
7
0
7
7
60
0
7
7
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _